Pilot study on the impact evaluation of atmospheric pollutants on UVB rays of wavelength 290-315 nm reaching earth’s surface and its effects on vitamin D synthesis among school students.
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Serum 25 (OH) Vitamin D levels, measured by chemiluminescence.
Study Overview
Brief Summary
This pilot study aims to evaluate the impact of atmospheric pollutants on the intensity of ultraviolet B (UVB) rays (wavelength 290–315 nm) reaching the Earth’s surface and to examine their consequent effect on vitamin D synthesis among school-going children. The study is a collaborative effort between the Department of Pediatric Endocrinology, AIIMS New Delhi, and the Society for Endocrine Health Care of Elderly, Adolescents and Children (SEHEAC). By correlating environmental data on air quality and UVB irradiance with serum vitamin D levels in participants, the study seeks to explore how pollution-mediated attenuation of UVB rays may contribute to hypovitaminosis D. The findings are expected to provide preliminary evidence for broader epidemiological studies and inform public health strategies targeting vitamin D deficiency in pediatric populations.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Masking
- None
Eligibility Criteria
- Ages
- 12.00 Year(s) to 16.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Cases: Class 9 students of both genders studying in a government school (12-16 year old children)
- •Controls: Class 8 students of both genders studying in a government school (12-16 year old children).
Exclusion Criteria
- •Subjects with any chronic illness
- •Those on medications that interfere with the evaluation of bone mineral metabolic parameters like anticonvulsant, antitubercular drugs, barbiturates and steroids.
- •Use of sunscreens
- •Using vitamin D or calcium supplements in last 3 months
- •Skin disease
- •Refusal to consent.
Outcomes
Primary Outcomes
Serum 25 (OH) Vitamin D levels, measured by chemiluminescence.
Time Frame: 4 monthly: in the Summer season (April- May), Rainy season (August-September), Winter Season (January-February)
Secondary Outcomes
- Correlation between AQI index and Serum 25 (OH) Vitamin D levels
Investigators
Dr. Rajni Sharma
All India Institute of Medical Sciences