Pilot study on the impact evaluation of atmospheric pollutants on UVB rays of wavelength 290-315 nm reaching earth’s surface and its effects on vitamin D synthesis among school students.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Serum 25 (OH) Vitamin D levels, measured by chemiluminescence.
研究概览
简要总结
This pilot study aims to evaluate the impact of atmospheric pollutants on the intensity of ultraviolet B (UVB) rays (wavelength 290–315 nm) reaching the Earth’s surface and to examine their consequent effect on vitamin D synthesis among school-going children. The study is a collaborative effort between the Department of Pediatric Endocrinology, AIIMS New Delhi, and the Society for Endocrine Health Care of Elderly, Adolescents and Children (SEHEAC). By correlating environmental data on air quality and UVB irradiance with serum vitamin D levels in participants, the study seeks to explore how pollution-mediated attenuation of UVB rays may contribute to hypovitaminosis D. The findings are expected to provide preliminary evidence for broader epidemiological studies and inform public health strategies targeting vitamin D deficiency in pediatric populations.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 12.00 Year(s) 至 16.00 Year(s)(—)
- 性别
- All
入选标准
- •Cases: Class 9 students of both genders studying in a government school (12-16 year old children)
- •Controls: Class 8 students of both genders studying in a government school (12-16 year old children).
排除标准
- •Subjects with any chronic illness
- •Those on medications that interfere with the evaluation of bone mineral metabolic parameters like anticonvulsant, antitubercular drugs, barbiturates and steroids.
- •Use of sunscreens
- •Using vitamin D or calcium supplements in last 3 months
- •Skin disease
- •Refusal to consent.
结局指标
主要结局
Serum 25 (OH) Vitamin D levels, measured by chemiluminescence.
时间窗: 4 monthly: in the Summer season (April- May), Rainy season (August-September), Winter Season (January-February)
次要结局
- Correlation between AQI index and Serum 25 (OH) Vitamin D levels
研究者
Dr. Rajni Sharma
All India Institute of Medical Sciences
