Reversing peripheral nerve dysfunction after spinal cord injury

Not Applicable

Recruiting

• Conditions: spinal cord injury; Neurological - Other neurological disorders; Injuries and Accidents - Other injuries and accidents

• Registration Number: ACTRN12618001770257
• Lead Sponsor: Austin Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-10-29
• Last Update Posted: 7 March 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

1. Complete or incomplete tetraplegia with C5 – C7 motor neurological level
2. Assessed as suitable for nerve transfer surgery by the surgical and occupational therapy team at the Upper Limb Program Multidisciplinary Clinic at Austin Health
3. Consent to nerve transfer surgery and intra-operative nerve and muscle biopsies after being fully informed about expected outcomes, potential risks, surgical procedure, recovery time, postoperative therapy commitments.
4. Able to comply with therapy protocols pre-operatively

Exclusion Criteria

1. Accompanying head injury, brachial plexus or peripheral nerve injury at the time of, or preceding the spinal cord injury
2. Any other pre-existing neurological condition
3. Cognitive impairment limiting ability to consent to surgery or comply with postoperative rehabilitation
4. Skeletal or joint injury signifcantly limiting passive range of movement across a joint relevant to the proposed nerve transfer
5. Contraindications to functional electrical stimulation

Study & Design

• Study Type: Interventional
• Study Design: Not specified