High concentration oxygen in Chronic Obstructive Pulmonary Disease (COPD): Study 2

Completed

• Conditions: COPD; Respiratory - Chronic obstructive pulmonary disease

• Registration Number: ACTRN12615001056583
• Lead Sponsor: Medical Research Institute of New Zealand

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-10-07
• Study Completion: 2017-05-18
• Last Update Posted: 14 June 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

COPD, as diagnosed by a doctor.

Exclusion Criteria

1. Baseline transcutaneous carbon dioxide of greater than or equal to 60mmHg
2. FEV1:FVC ratio >0.7
3. Age under 16 years
4. A diagnosis of bronchiectasis
5. Morbid obesity (with a body mass index of greater than or equal to 40)
6. Inability to match FEV1 percentage predicted to a participant that took part in the bronchiectasis oxygen study*
7. Any other condition which, at the investigator’s discretion, is believed may present a safety risk or impact the feasibility of the study or the study results.

*This study is designed to allow for comparison of results to a study of similar design in patients with bronchiectasis (ACTRN12615000971538). Participants will therefore be matched by FEV1 to the participants in the bronchiectasis study (the COPD participant must have an FEV1 percentage predicted within an absolute value of 5% of the FEV1 percentage predicted for the bronchiectasis patient (values inclusive)). An exception to this is for the three bronchiectasis participants that had FEV1 percentage predicted values of 109% or higher, who are to be matched with COPD participants with an FEV1 percent predicted of 80% or over (i.e. participants in the mildest COPD severity category based on FEV1).

Study & Design

• Study Type: Interventional
• Study Design: Not specified