Comparative study on the efficacy of high versus low fluence of 595-nm pulsed dye laser for knee arthroplasty scar preventio

Phase 4

Recruiting

• Conditions: Patients who have undergone bilateral knee arthroplasty within one month; Scar; PDL; Purpuric

• Registration Number: TCTR20230427003
• Lead Sponsor: Faculty of Medicine Siriraj Hospital, Mahidol University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-04-27
• Last Update Posted: 19 August 2024
• Study Completion: 2024-12-04

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1. Being a Thai person of Asian descent
2. Those who have undergone bilateral knee arthroplasty surgery within 1 month or have an appointment to have bilateral knee arthroplasty surgery within one month before the operation.
3. Volunteers who voluntarily agree to participate in the project and agree to take pictures of the surgical scars

Exclusion Criteria

1. Volunteers who had dermatitis or skin infection at the treatment site.
2. Volunteers with a history of knee arthroplasty surgery wound infection
3. Volunteers with severe medical conditions or those receiving immunosuppressants such as steroids or chemotherapy drugs
4. Volunteers with hypertrophic scars or keloids in the area to be treated before knee replacement surgery
5. Volunteers with mental disorders whom a psychiatrist has diagnosed.
6. Subjects with a history of photosensitive skin

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Scar elevation Before, 4 weeks, 8 weeks, 12 weeks, 20 weeks, 32 weeks after first treatment Antera 3D imaging system

Secondary Outcome Measures

Name	Time	Method
Vancouver scar scale Before, 4 weeks, 8 weeks, 12 weeks, 20 weeks, 32 weeks after first treatment Clinical evaluation