The dynamics and pathophysiological function of endothelial microparticles in sepsis.
Not Applicable
- Conditions
- sepsis
- Registration Number
- JPRN-UMIN000032617
- Lead Sponsor
- Tohoku University Hospital
- Brief Summary
ThePECAM+ or VE-cadherin+ EDEVs on admission was significantly higher in the septic-shock group than the sepsis group (p = 0.043 or 0.004). Furthermore, multivariable analysis revealed that the numbers of PECAM+ and VE-cadherin+ EDEVs were independently higher in the septic-shock group than in the sepsis group. The abundance of all types was significantly higher in the sepsis and septic-shock groups compared with the non-sepsis group.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 102
Inclusion Criteria
Not provided
Exclusion Criteria
failure to obtain informed consent infection with unknown onset supported by ECMO (extracorporeal membrane oxygenation) the initiation of renal replacement therapy before the entry
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The number of circulating EMPs during IC
- Secondary Outcome Measures
Name Time Method