Pilot Study of Continuing Aspirin Versus Switching to Clopidogrel After Stroke or Transient Ischemic Attack

Phase 1

Withdrawn

• Conditions: Clopidogrel; Transient Ischemic Attack; Stroke; Aspirin

• Registration Number: NCT00363753
• Lead Sponsor: University of California, San Diego

Brief Summary

Pilot study of continuing aspirin versus switching to clopidogrel after stroke or transient ischemic attack.

Detailed Description

Pilot study of continuing aspirin versus switching to clopidogrel after stroke or transient ischemic attack.

Study Timeline

• Study Start: 2006-08
• Study First Submitted: 2006-08-10
• Study First Submitted QC: 2006-08-10
• Study First Posted: 2006-08-15
• Study Completion: 2007-03
• Status Verified: 2019-07
• Last Update Submitted: 2019-07-31
• Last Update Posted: 2019-08-02

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Age 18 and older.
• Stroke or transient ischemic attack (TIA) while taking aspirin within one week of consent.
• Women of child-bearing potential will be included only if there is a negative pregnancy test and they agree to birth control during the treatment period.

Exclusion Criteria

• Any medical indication for a specific antiplatelet agent (aspirin, clopidogrel, ticlopidine, aggrenox), or an indication for a combination of antiplatelet agents.
• Any medical indication for anticoagulation, except subcutaneous heparin for deep vein thrombosis prophylaxis.
• Allergy to aspirin or clopidogrel.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
mRS at three months.

Secondary Outcome Measures

Name	Time	Method
Incidence of stroke at three months, bleeding events.

Trial Locations

Locations (2)

UCSD Hillcrest; 🇺🇸 San Diego, California, United States

UCSD; 🇺🇸 San Diego, California, United States