Comparison between two ventilatory modes in reducing the days of mechanical ventilation and also assosciated complications.
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Prematurely born newborns with Respiratory distress syndrome
- Registration Number
- CTRI/2017/11/010439
- Lead Sponsor
- I
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 81
Inclusion Criteria
1 Neonates with congenital cyanotic heart diseases.
2 Neonates with major congenital malformations.
3 Neonates with air leak syndromes.
4 Neonates requiring High Frequency Oscillatory Ventilation (HFOV)
Exclusion Criteria
1.Neonates with congenital cyanotic heart diseases.
2.Neonates with major congenital malformations.
3.Neonates with air leak syndromes.
4.Neonates requiring High Frequency Oscillatory Ventilation (HFOV)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary outcome is to compare the time required to reach the weaning criteria assessed by volume targeted ventilation to pressure limited ventilation in prematurely born infants.Timepoint: At the time of extubation
- Secondary Outcome Measures
Name Time Method 1 Rate of failure <br/ ><br>2 Oxygenation Index at 6th hourly <br/ ><br>3 FiO2 to SpO2 ratio <br/ ><br>4 PaO2 to FiO2 ratio <br/ ><br>5 Episodes of hypocarbia at 2nd hourly <br/ ><br>6 Duration of mechanical ventilation <br/ ><br>7 Oxygen radicals <br/ ><br>8 Complications such as <br/ ><br>9 Broncho pulmonary dysplasia(BPD) <br/ ><br>10 Periventricular leukomalacia(PVL) <br/ ><br>11 Air leak syndrome <br/ ><br>12 Intraventricular Hemorrhage (IVH) <br/ ><br>13 Retinopathy of Prematurity (ROP) <br/ ><br>14 Mortality <br/ ><br>Timepoint: at the time of extubation and at the time of discharge