A Study on the efficacy and safety of Docetaxel plus Nedaplatin in patients with advanced non-small-cell lung cancer - A Study on the efficacy and safety of Docetaxel plus Nedaplatin in patients with advanced non-small-cell lung cancer

Shiga University of Medical Science0 个研究点目标入组 40 人开始时间: 2011年2月5日最近更新: 2023年10月17日

适应症

试验速览

阶段: 2 期
状态: 已完成
发起方: Shiga University of Medical Science
入组人数: 40

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

(Patients background) Enrolled patients:46 Male/Female=39/7, PS 0/1=27/19, IIIB/IV=20/27 Sq/Ad/NSCLC/AdSq=12/25/8/ Total cycles administered:144 cycles(mean:3.1 cycles) (Efficacy) CR/PR/SD/PD=0/24/11/11 Objective response rate 52.2% (24/46) (Safety) Grade 3- Leukopenia 29.2% Nausea/vomiting 3.5% Anorexia 4.2%

研究设计

研究类型: Interventional

入排标准

年龄范围: 20years-old 至 79years-old（—）
性别: All

入选标准

未提供

排除标准

•1. Allergy against polysorbert 80 or platinum-containing drugs 2. Severe complications (i.e. ischemic heart diseases required treatment, arrhythmia, myocardial infarction within 6 months, liver cirrhosis, uncontrolled diabetes,hemorrhagic tendency ) 3. Active infections 4. Massive pleural or pericardial effusion 5. Brain metastases with neurological symptoms. 6. Active simultaneous cancer 7. Active interstitial pneumonitis or its past history 8. Peripheral nerve disorder 9. Pregnant or lactating women 10. Other conditions not suitable for this study

研究者

发起方

Shiga University of Medical Science

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