Preventive effect of leg wrapping and leg elevation on hypotension induced by propofol
Not Applicable
Recruiting
- Conditions
- Not Applicable
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 442
Inclusion Criteria
Patients undergoing elective general anesthesia with American Society of Anesthesiologist's physical status ?(no systemic disease)-? (controlled systemic disease), aged 20-60 years.
Exclusion Criteria
severe cardiac/pulmonary/liver/renal disease, body mass index > 30 kg/m2, antihypertensive medication, uncontrolled hypertension, risk of hypersensitiity to propofol,allergic to the study durgs, patients whose legs cannot be wrapped (leg injury, leg prosthesis, ect.), patients wearing elastic stocking
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Systolic/diastolic blood pressure (mmHg)
- Secondary Outcome Measures
Name Time Method heart rate
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What physiological mechanisms explain leg wrapping and elevation in preventing propofol-induced hypotension?
How does leg wrapping compare to vasopressors like phenylephrine for managing propofol-related hypotension in anesthesia?
Which biomarkers correlate with reduced hypotension risk during leg elevation and wrapping in propofol sedation?
What are the safety concerns and management strategies for leg wrapping/elevation in propofol-induced hypotension trials?
Are there alternative non-pharmacological interventions to leg wrapping for preventing propofol-induced hypotension in surgical patients?