Postprandial Lipemia and Glycemia Following a High-Fat Meal
Not Applicable
Completed
- Conditions
- HypercholesterolemiaLipid DisorderPostprandial Hyperglycemia
- Interventions
- Dietary Supplement: Mushroom Powder
- Registration Number
- NCT05619952
- Lead Sponsor
- State University of New York at Buffalo
- Brief Summary
The goal of this clinical trial is to determine the acute effects on postprandial lipemia and glycemia by supplementing a high-fat meal with either white button (WB) or shiitake (SH) mushroom powder in relatively healthy adults, aged 18 to 35.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 16
Inclusion Criteria
- generally healthy
- non-diabetic
- normal to mildly hypercholesterolemic (Total Cholesterol 200-239 mg/dL and LDL-C 130-159 mg/dL)
- have BMI <30 or BF% (men <25%, women <32%)
- no known disease of the liver or gallbladder
- no documented problems with fat metabolism
- normal lipemic response to a lipid challenge
- No known mushroom allergy
Exclusion Criteria
- diabetic
- pregnant
- BMI >30
- liver disease
- gallbladder disease
- mushroom allergy
- lipid disorder
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Shiitake Mushroom Mushroom Powder 368.5 grams of irradiated ground beef patty (80/20 lean mass to fat ratio) + 14 grams Shiitake mushroom powder, and a Wegmans Food Market Brand Big Hawaiian bun White Button Mushroom Mushroom Powder 368.5 grams of irradiated ground beef patty (80/20 lean mass to fat ratio) + 14 grams white button mushroom powder, and a Wegmans Food Market Brand Big Hawaiian bun
- Primary Outcome Measures
Name Time Method Postprandial Glycemia Baseline, up to 6 hours postprandial blood glucose
Postprandial Lipemia Baseline, up to 6 hours postprandial Total cholesterol, LDL, HDL, triglycerides
- Secondary Outcome Measures
Name Time Method