Comparison of Partial Removal and Total Removal of the Corneal Epithelium on Keratoconus
Phase 2
Completed
- Conditions
- Keratoconus
- Registration Number
- NCT01809977
- Lead Sponsor
- Isfahan University of Medical Sciences
- Brief Summary
The purpose of this study is to determine which surgical method makes less corneal haze
- Detailed Description
Keratoconus is an asymmetric, bilateral, progressive non-inflammatory ectasia of the cornea. The investigators evaluate whether partial removal versus total removal of the corneal epithelium can lead to less corneal haze and better visual outcomes.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 22
Inclusion Criteria
- Age between 16-40 years
- axial topography consistent with keratoconus
- minimum corneal thickness more than 400 µm and a progression of keratoconus in past 12 months
Exclusion Criteria
- history of ocular herpes or non-healing corneal ulcers
- subjects with current ocular infection
- severe preoperative corneal haze or scar
- severe ocular surface disease
- autoimmune diseases
- pregnant women
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Best corrected visual acuity at six months after surgery determining corrected visual acuity in partial removal versus total removal of the corneal epithelium
- Secondary Outcome Measures
Name Time Method Corneal optical density at six months after surgery Corneal optical density was assessed by Scheimpflug densitometry
Trial Locations
- Locations (1)
Feyz university hospital
🇮🇷Isfahan, Iran, Islamic Republic of
Feyz university hospital🇮🇷Isfahan, Iran, Islamic Republic of