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The Effect of Feeding Infant Formula Containing Prebiotics and/or Probiotics

Not Applicable
Terminated
Conditions
Metabolomics
Registration Number
NCT02948114
Lead Sponsor
Mead Johnson Nutrition
Brief Summary

The study is intended to evaluate the microorganisms found in infant stools when consuming study formulas containing prebiotics and/or probiotics compared to infants consuming mother's own breast milk.

Detailed Description

Not available

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
2
Inclusion Criteria
  • Singleton, 10-14 days of age at registration/randomization
  • Term infant with birth weight of 2500 grams or more from a vaginal birth
  • Formula feeding infants must be on formula for at least 3 days
  • Human milk fed infants must have received mother's own breast milk from 1 day of age to study registration and mother has intention to exclusively provide mother's own breast milk for the duration of the study
  • Signed informed consent
Exclusion Criteria
  • History of underlying metabolic or chronic disease or immune compromised
  • Feeding difficulties or formula intolerance

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Change in fecal microbiota3.5 months
Secondary Outcome Measures
NameTimeMethod
Recall of infant formula usage at each study visitUp to 3.5 months
Recall of gastrointestinal tolerance questionnaire at each study visitUp to 3.5 months
Medically-confirmed adverse events collected throughout the study periodUp to 3.5 months
Body Length measured at each study visitUp to 3.5 months
Body Weight measured at each study visitUp to 3.5 months
Head circumference measured at each study visitUp to 3.5 months

Trial Locations

Locations (1)

Hainan Province Women & Children Hospital

🇨🇳

Haikou, Hainan, China

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