Investigating the Impact of Nudging Cardiologists to Prescribe Guideline-directed Medical Therapy in Heart Failure Patients

Not Applicable

Recruiting

• Conditions: Heart Failure

• Registration Number: NCT06844006
• Lead Sponsor: Medisch Spectrum Twente

Brief Summary

This study investigates the impact of a nudge-based intervention on improving guideline directed medical therapy (GDMT) prescription among cardiologists. Using a stepped wedge randomized controlled trial design, we assess whether digital decision support-leveraging home monitoring and clinical data-enhances adherence to guideline-recommended medication titration. The primary outcomes include HF related hospitalization rates and all cause mortality.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-06-13
• Study First Submitted: 2025-02-19
• Study First Submitted QC: 2025-02-19
• Study First Posted: 2025-02-25
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-06
• Last Update Posted: 2025-03-07
• Primary Completion: 2027-04-30
• Study Completion: 2028-08-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 1320

Inclusion Criteria

• All heart failure diagnoses
• >18 years

Exclusion Criteria

• Not understanding the Dutch Language.
• Allergies that make uptitration impossible.
• Admission to hospice or palliative care.
• Severe psychological disorders.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
HF related hospitalization	From enrollment to the end of the design (15 months).	The frequency of HF related hospitalization and duration of the hospitalization.
All cause death	All cause death rate during the 15 month duration of the study.

Trial Locations

Locations (1)

Medisch Spectrum Twente; 🇳🇱 Enschede, Overijssel, Netherlands