The Effect of Extracorporeal Shock Wave Therapy on Carpal Tunnel Syndrome
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Carpal Tunnel Syndrome
- Sponsor
- Tri-Service General Hospital
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Change from baseline of pain on1st, 2nd, 4th, 8th,12th and 16th weeks after treatment.
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
The shock wave is a new and potential intervention for the reinnervation of peripheral nerve. The purpose of this study was to assess the effect of extracorporeal shock wave therapy on carpal tunnel syndrome.
Detailed Description
Recently, many studies show the potential effect of shock wave for the reinnervation for peripheral neuropathy in the animal mode. Only one study reveal the potential benefit of shock wave in patients with carpal tunnel syndrome. Althouh its expressive finding, the number of cases is relatively too small to make a conclusive remark. Large and well-designed study would expand the new field.
Investigators
Yung-Tsan Wu
Attending Physician
Tri-Service General Hospital
Eligibility Criteria
Inclusion Criteria
- •Outpatient subjects who had typical symptoms and signs of CTS, such as positive Tinel's sign or Phalen's test and numbness/tingling in at least two of the first, second, and third digits and were all confirmed by electrophysiological study, were considered and enrolled.
Exclusion Criteria
- •The patients who had conditions mimicking CTS, such as cervical radiculopathy, polyneuropathy, brachial plexopathy, thoracic outlet syndrome or who had previous wrist surgery or steroid injection for CTS, were all excluded.
Outcomes
Primary Outcomes
Change from baseline of pain on1st, 2nd, 4th, 8th,12th and 16th weeks after treatment.
Time Frame: Pre-treatment, 1st, 2nd, 4th, 8th, 12th and 16th weeks after treatment.
Using the Visual analog scale (VAS) to measure the pain scale before treatment and multiple time frame after treatment.
Secondary Outcomes
- Change from baseline in finger pinch on 1st, 2nd, 4th, 8th, 12th and 16th weeks after treatment.(Pre-treatment, 1st, 2nd, 4th, 8th,12th and 16th weeks after treatment.)
- Change from baseline in severity of symptoms and functional status on 1st, 2nd, 4th, 8th,12th and 16th weeks after treatment.(Pre-treatment, 1st, 2nd, 4th, 8th,12th and 16th weeks after treatment.)
- Change from baseline in cross-sectional area of the median nerve on 1st, 2nd, 4th, 8th, 12th and 16th weeks after treatment.(Pre-treatment, 1st, 2nd, 4th, 8th, 12th and 16th weeks after treatment.)
- Change from baseline in conduction velocity, ampliture of median nerve on 1st, 2nd, 4th, 8th,12th and 16th weeks after treatment.(Pre-treatment, 1st, 2nd, 4th, 8th,12th and 16th weeks after treatment.)