Validation of Cellular Tests for Lyme borreliosis

Academic Medical Center0 个研究点目标入组 585 人开始时间: 待定最近更新: 2024年6月11日

试验速览

暂无简介。

•1. EITHER report a physician-confirmed erythema migrans (EM) with a diameter larger than 5 cm and that has been present for less than 3 months
•2. OR have a confirmed diagnosis of early or late (disseminated) Lyme borreliosis
•HEALTHY CONTROLS
•No specific inclusion criteria
•CROSS-REACTIVE CONTROLS
•One of several infectious or inflammatory diseases (Epstein-Bar virus/cytomegalovirus, leptospirosis, syphilis, auto-immune diseases), with criteria depending on the disease in question
•OUTPATIENT COHORT
•all patients presenting at the specialized Lyme centers of the AMC or Radboudumc.

•Cases must not have started their course of antibiotic treatment more than 4 days (inclusion through self-report on the Tekenradar.nl-website) or more than 7 days (inclusion through participating hospitals) before inclusion.
•HEALTHY CONTROLS
•Exclusion criteria are current Lyme borreliosis and having certain factors that may impair immunity (e.g., immunosuppressants or known immunodeficiency)
•CROSS-REACTIVE CONTROLS
•Exclusion criteria are ever having had an episode of Lyme borreliosis, recent tick bite, more than one potentially cross-reactive condition, having certain factors that may impair immunity (see above).
•OUTPATIENT COHORT
•There are no specific exclusion criteria.

发起方

Academic Medical Center