A study to compare different parameters following opioid (medications that decrease pain) free technique versus standard technique of general anesthesia (using opioids) for removal of gall bladder .
Phase 4
- Conditions
- Health Condition 1: K80- CholelithiasisHealth Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2022/11/046967
- Lead Sponsor
- CMS and GTB Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients giving consent for the study and aged 20-55 years belonging to ASA grade I or II scheduled for elective laparoscopic cholecystectomy under general anaesthesia
Exclusion Criteria
1.Patients with known case of cardiovascular, pulmonary, psychological or neurological diseases
2.Patients who are known to be epileptic
3.Patients who have signs and symptoms of raised intracranial tension
4.Patients with known allergies to the study drugs
5.Patients with abnormalities like heart block, left bundle branch block
6.Obese patients (BMI = 30kg/m2)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The time taken for extubation between the opioid free anesthesia versus standard balanced anesthesia groupTimepoint: The time to extubation, which is the time taken from the injection of reversal to the extubation of endotracheal tube which will be counted in minutes (the same has been used for sample size calculation as well).
- Secondary Outcome Measures
Name Time Method To compare between the two groups- <br/ ><br>1. Hemodynamic parameters at the time of inubation <br/ ><br>2. Hemodynamic parameters intraoperatively <br/ ><br>3. Hemodynamic parameters at the time of extubation <br/ ><br>4. Post-operative recovery using modified Aldrete score (Anexure III) <br/ ><br>5. Post-operative pain using Numeric Rating Scale (NRS) (Anexure IV) <br/ ><br>6. Total dose of rescue analgesia required in 24 hours <br/ ><br>7. Any adverse effects <br/ ><br>8. To assess the quality of post operative pain using QoR-15 score <br/ ><br>Timepoint: 24 hours post operatively