The Pathogenesis and Prognostic Factors of Lymphoma
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 2,000
- 试验地点
- 1
- 主要终点
- OS
研究概览
简要总结
The aim of this study is to describe the clinical and genetic characteristics of Chinese lymphoma patients, and to explore the relationship between those characteristics and phatogenesis.
详细描述
Lymphoma is a highly common malignant tumor in Asia. This study aims to observe and describe the clinical and genetic charateristics of Chinese lymphoma patients, and to explore the relationship between those charateristics and pathogenesis and prognostic factors in the real-world population. This study is a non-interventional real world, observational study and all registered data are collected from real clinical practice cases. The medical data includes patient demographic, tumor characteristics, laboratory examination, history of treatments, adverse reactions, efficacy results and possible prognostic factors.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with pathological diagnosis of lymphoma (including Hodgkin lymphoma and non-Hodgkin lyphoma, eg. THRLBCL, DLBCL, MZL, CLL/SLL...) from 2007 to
- •Patients with complete diagnostic, treatment and follow-up records.
- •Fully comprehension and signature of the informed consent form (ICF) for participation.
排除标准
- •Those who refuse to use reliable methods of contraception during pregnancy, lactation or age-appropriate period.
- •Severe mental illness.
- •Patients deemed unsuitable for inclusion by the investigator.
结局指标
主要结局
OS
时间窗: Baseline up to data cut-off (Up to approximately 20 years)
Overall survival (OS) refers to the time from receiving the first dose to death from any cause
次要结局
- PFS(Baseline up to data cut-off (Up to approximately 20 years))
研究者
Peng Liu
Chief of Hematology department
Shanghai Zhongshan Hospital