Impact of New Anthropometric Indices on Outcomes After Cardiac Surgery
试验速览
- 阶段
- 不适用
- 入组人数
- 240
- 主要终点
- permanent rhythm device insertion
研究概览
简要总结
Obesity is associated with a number of risk factors for cardiovascular disease. Body mass index (BMI) is the most commonly recommended and used anthropometric measure to classify general obesity in clinical and epidemiological studies. It is widely accepted that obesity increases the risk of heart disease and is thought to be a risk factor for adverse outcomes after cardiac surgery. However, recent studies show paradoxical results, wherein obese patients can experience fewer adverse events and lower mortality than patients with normal-low body mass index(BMI) . The discriminative capacity of BMI has been criticized because it cannot distinguish muscle mass from fat mass, or reflect fat distribution . Alternatively, abdominal obesity indices, such as waist circumference (WC) and waist-to-height ratio (WHtR), have been suggested to be better predictor of cardiometabolic abnormalities because they modulate the limitation of BMI. However, they were insufficient in studies.For this reason, scientists turned to find a new anthropometric formula that could better detect obesity-related mortality and morbidity and they developed 2 new methods. Body Shape İndex (ABSI) is calculated using waist circumference, BMI and height parameters. Body Roundness İndex (BRI) is calculated using waist circumference and height parameters. These new indices may reflect visceral adiposity and strongly predict cardiovascular risk, postsurgical outcomes and resource utilisation.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •open heart surgery
- •voluntary patients
排除标准
- •emergency surgery
- •off-pump or robotic surgery
- •surgery requiring deep hypothermic circulatory arrest
- •reluctant patients
结局指标
主要结局
permanent rhythm device insertion
时间窗: within 30 days of the procedure
Number of Patients requiring insertion of a permanent device
cardiac arrest
时间窗: within 30 days of the procedure
number of patients with cardiac arrest
postoperative stroke
时间窗: within 30 days of the procedure
Number of patients with postoperative stroke
mortality
时间窗: within 30 days of the procedure
Number of death at 30 days after surgery
new atrial fibrillation/flutter
时间窗: within 30 days of the procedure
Number of Partients with new atrial fibrillation/flutter
次要结局
- intensive care unit (ICU) readmissions(within 30 days of the procedure)
- prolonged ventilation(within 30 days of the procedure)
- sepsis /deep sternal infection(within 30 days of the procedure)
- total intensive care unit (ICU) hours(within 30 days of the procedure)
- renal failure / renal dialysis(within 30 days of the procedure)
- pulmonary complications(within 30 days of the procedure)
研究者
MERVE SAHINGOZ
Principal Investigator
TC Erciyes University
