跳至主要内容
临床试验/NCT05403294
NCT05403294Unknown不适用

Impact of New Anthropometric Indices on Outcomes After Cardiac Surgery

TC Erciyes University0 个研究点目标入组 240 人开始时间: 2022年7月27日最近更新:
适应症

试验速览

阶段
不适用
入组人数
240
主要终点
permanent rhythm device insertion

研究概览

简要总结

Obesity is associated with a number of risk factors for cardiovascular disease. Body mass index (BMI) is the most commonly recommended and used anthropometric measure to classify general obesity in clinical and epidemiological studies. It is widely accepted that obesity increases the risk of heart disease and is thought to be a risk factor for adverse outcomes after cardiac surgery. However, recent studies show paradoxical results, wherein obese patients can experience fewer adverse events and lower mortality than patients with normal-low body mass index(BMI) . The discriminative capacity of BMI has been criticized because it cannot distinguish muscle mass from fat mass, or reflect fat distribution . Alternatively, abdominal obesity indices, such as waist circumference (WC) and waist-to-height ratio (WHtR), have been suggested to be better predictor of cardiometabolic abnormalities because they modulate the limitation of BMI. However, they were insufficient in studies.For this reason, scientists turned to find a new anthropometric formula that could better detect obesity-related mortality and morbidity and they developed 2 new methods. Body Shape İndex (ABSI) is calculated using waist circumference, BMI and height parameters. Body Roundness İndex (BRI) is calculated using waist circumference and height parameters. These new indices may reflect visceral adiposity and strongly predict cardiovascular risk, postsurgical outcomes and resource utilisation.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • open heart surgery
  • voluntary patients

排除标准

  • emergency surgery
  • off-pump or robotic surgery
  • surgery requiring deep hypothermic circulatory arrest
  • reluctant patients

结局指标

主要结局

permanent rhythm device insertion

时间窗: within 30 days of the procedure

Number of Patients requiring insertion of a permanent device

cardiac arrest

时间窗: within 30 days of the procedure

number of patients with cardiac arrest

postoperative stroke

时间窗: within 30 days of the procedure

Number of patients with postoperative stroke

mortality

时间窗: within 30 days of the procedure

Number of death at 30 days after surgery

new atrial fibrillation/flutter

时间窗: within 30 days of the procedure

Number of Partients with new atrial fibrillation/flutter

次要结局

  • intensive care unit (ICU) readmissions(within 30 days of the procedure)
  • prolonged ventilation(within 30 days of the procedure)
  • sepsis /deep sternal infection(within 30 days of the procedure)
  • total intensive care unit (ICU) hours(within 30 days of the procedure)
  • renal failure / renal dialysis(within 30 days of the procedure)
  • pulmonary complications(within 30 days of the procedure)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

MERVE SAHINGOZ

Principal Investigator

TC Erciyes University

相似试验

Impact of New Anthropometric Indices on Outcomes... | 临床试验