Change of Retinal Vessel Diameter in Branch Retinal Vein Occlusion After Intravitreal Bevacizumab Injection
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Branch Retinal Vein Occlusion
- Sponsor
- Kyungpook National University Hospital
- Enrollment
- 25
- Locations
- 1
- Primary Endpoint
- Unoccluded retinal vessel diameter of Branch Retinal Vein Occlusion
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
The authors investigated the consecutive change of retinal vessel's diameter in affected eye and fellow eye of Branch Retinal Vein Occlusion.
Detailed Description
Twenty five consecutive patients who had undergone intravitreal bevacizumab injection for Branch Retinal Vein Occlusion with macular edema were included in this study. All subjects were enrolled between April, 2012 and April, 2013 in the Department of Ophthalmology, Kyungpook National University Hospital.
Investigators
Dong Ho Park
Clinical professor
Kyungpook National University Hospital
Eligibility Criteria
Inclusion Criteria
- •Best-corrected visual acuity less than 20/40
- •Central subfield macular thickness (CSMT) 300 μm or greater on spectral-domain optical coherence tomography
Exclusion Criteria
- •Patients with recurrent BRVO
- •History of previous treatments for BRVO including vitreoretinal surgery, intravitreal injection, subtenon injection or laser photocoagulation
- •Patients with diabetes or dyslipidemia
- •IOP ≥ 22mmHg, treatment for glaucoma, a family history of glaucoma, or optic neuropathy
- •High myopia (\<-6 Diopters), high hyperopia (\>6 Diopters) or a history of refractive surgeries
- •Co-existing retinal disease other than BRVO
- •Corneal diseases include ulcer, keratoconus and a history of corneal laceration
- •Cataract and other media opacities resulting in visual impairment or poor fundus images
Outcomes
Primary Outcomes
Unoccluded retinal vessel diameter of Branch Retinal Vein Occlusion
Time Frame: 0, 1, 3, and 6 months
To evaluate the change of unoccluded retinal vessel diameter in affected eye of Branch Retinal Vein Occlusion and unaffected fellow eye.