Retinal Vessel Diameter in Branch Retinal Vein Occlusion

Completed

• Conditions: Branch Retinal Vein Occlusion

• Registration Number: NCT02215109
• Lead Sponsor: Kyungpook National University Hospital

Brief Summary

The authors investigated the consecutive change of retinal vessel's diameter in affected eye and fellow eye of Branch Retinal Vein Occlusion.

Detailed Description

Twenty five consecutive patients who had undergone intravitreal bevacizumab injection for Branch Retinal Vein Occlusion with macular edema were included in this study. All subjects were enrolled between April, 2012 and April, 2013 in the Department of Ophthalmology, Kyungpook National University Hospital.

Study Timeline

• Study Start: 2012-04
• Study First Submitted: 2014-08-11
• Study First Submitted QC: 2014-08-12
• Study First Posted: 2014-08-13
• Primary Completion: 2016-07
• Status Verified: 2016-08
• Study Completion: 2016-08
• Last Update Submitted: 2016-08-29
• Last Update Posted: 2016-08-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• Best-corrected visual acuity less than 20/40
• Central subfield macular thickness (CSMT) 300 μm or greater on spectral-domain optical coherence tomography

Exclusion Criteria

• Patients with recurrent BRVO
• History of previous treatments for BRVO including vitreoretinal surgery, intravitreal injection, subtenon injection or laser photocoagulation
• Patients with diabetes or dyslipidemia
• IOP ≥ 22mmHg, treatment for glaucoma, a family history of glaucoma, or optic neuropathy
• High myopia (<-6 Diopters), high hyperopia (>6 Diopters) or a history of refractive surgeries
• Co-existing retinal disease other than BRVO
• Corneal diseases include ulcer, keratoconus and a history of corneal laceration
• Cataract and other media opacities resulting in visual impairment or poor fundus images

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Unoccluded retinal vessel diameter of Branch Retinal Vein Occlusion	0, 1, 3, and 6 months	To evaluate the change of unoccluded retinal vessel diameter in affected eye of Branch Retinal Vein Occlusion and unaffected fellow eye.

Trial Locations

Locations (1)

Dong Ho Park; 🇰🇷 Daegu, Kyungsangpookdo, Korea, Republic of