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Cord Blood 25(oh)-Vitamin D Level in Preterm Infants and Associated Morbidities

Completed
Conditions
Respiratory Distress Syndrome
Registration Number
NCT01812681
Lead Sponsor
Dr. Sami Ulus Children's Hospital
Brief Summary

Experimental and observational studies have shown that vitamin D deficiency may be associated with an increased risk for non-bone diseases and/or abnormal development for the other systems of fetus. The aim of this study is to determine the relationship between cord blood 25-hydroxyvitamin D (25 (OH) D) concentrations and the subsequent risk of morbidities including RDS, PDA, NEC, BPD AND ROP in preterm infants.

Detailed Description

It was shown that vitamin D play important role in the pathogenesis of long term morbidities of newborn. Experimental and observational studies have shown that vitamin D deficiency may be associated with an increased risk for non-bone diseases and/or abnormal development for the other systems of fetus. The aim of this study is to determine the relationship between cord blood 25-hydroxyvitamin D (25 (OH) D) concentrations and the subsequent risk of morbidities including RDS, PDA, NEC, BPD AND ROP in preterm infants.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
81
Inclusion Criteria
  • infants <32 weeks of gestational age
Exclusion Criteria
  • infants with major congenital abnormality
  • infants >32 weeks of gestational age

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Respiratory Distress Syndromethree days

The association of vitamin D level with respiratory distress syndrome

Secondary Outcome Measures
NameTimeMethod
Sepsisfour weeks

Association of vitamin D level with sepsis

Trial Locations

Locations (1)

Sami Ulus CH

🇹🇷

Ankara, Turkey

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