Adductor-Canal-Blockade Versus the Femoral Nerve Block Effect on Muscle Strength and Mobilization in Healthy Volunteers

Phase 4

Completed

• Conditions: Muscle Strength; Healthy Volunteers
• Interventions: Procedure: Adductor-Canal-Blockade; Procedure: The femoral nerve block; Procedure: Placebo

• Registration Number: NCT01449097
• Lead Sponsor: Rigshospitalet, Denmark

Brief Summary

The aim of this study is to investigate the efficacy of the Adductor-Canal-Blockade versus the femoral nerve block versus placebo on muscle strength in healthy volunteers. The investigators hypothesize that the Adductor-Canal-Blockade results in a lesser reduction of the quadriceps muscle strength compared to the femoral nerve block.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-10
• Study First Submitted: 2011-10-06
• Study First Submitted QC: 2011-10-06
• Study First Posted: 2011-10-07
• Primary Completion: 2011-11
• Study Completion: 2011-11
• Status Verified: 2011-12
• Last Update Submitted: 2011-12-21
• Last Update Posted: 2011-12-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 12

Inclusion Criteria

• written informed consent
• ASA 1
• BMI > 18 og < 25

Exclusion Criteria

• Can not cooperate to the exam
• Do not speak or understand Danish
• Drug allergy
• Alcohol or drug abuse
• Daily consumption of analgetics on prescription
• Any drug intake within the last 48 hours
• Neuromuscular defects in the femoral nere, the obturator nerve or the muscles of the thigh.
• Previous surgery or trauma to the lower limb
• Diabetes Mellitus
• Intake of steroids, except steroids for inhalation
• Physical exercise within the last 24 hours prior to Day 1 and 2 of the study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Adductor-Canal-Blockade	Adductor-Canal-Blockade	-
The femoral nerve block	The femoral nerve block	-
Placebo	Placebo	-

Primary Outcome Measures

Name	Time	Method
the difference in quadriceps muscle strength between the Adductor-Canal-Blockade and placebo	0-6 hours

Secondary Outcome Measures

Name	Time	Method
The difference in quadriceps muscle strength between the Adductor-Canal-Blockade and the femoral nerve block	0-6 hours
The difference in quadriceps muscle strength between the placebo and the femoral nerve block	0-6 hours
The difference in adductor muscle strength between the groups	0-6 hours
The difference in mobilization between the groups	0-6 hours

Trial Locations

Locations (1)

Department of Anaesthesia, Centre of Head and Orthopaedics, Copenhagen University Hospital, Rigshospitalet; 🇩🇰 Copenhagen, Denmark