Effect of rectal acetaminophen on patent ductus arteriusus (PDA) in premature neonates
Not Applicable
- Conditions
- Patent ductus arteriosus.Patent ductus arteriosus
- Registration Number
- IRCT2017020732449N1
- Lead Sponsor
- Kermanshah University of Medical Scienses
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 16
Inclusion Criteria
Inclusion criteria : premature neonates with gestational age less than 35 weeks and post natal age less than 14 days with patent ductus arteriosus.
Exclusion criteria: neonate death; elevated liver enzimes more than 3 folds; G6PD; hyperbilirubinemia that required blood exchange; renal failure and NEC.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Size of patent ductus arteriosus. Timepoint: Before and after 3 days tratment period. Method of measurement: Echocardiography.
- Secondary Outcome Measures
Name Time Method Renal function test. Timepoint: before and after 3 days treatment. Method of measurement: laboratory.;G6PD Activity. Timepoint: before begining of treatment. Method of measurement: alaboratory.;Liver enzimes. Timepoint: befor and after 3days treatment oeriod. Method of measurement: laboratory.;Bilirubin. Timepoint: before and after 3 days treatment. Method of measurement: laboratory.