Amount of inhaled gas requirement
Phase 4
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2024/05/067486
- Lead Sponsor
- Dr Sunita kumari
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA 1 or 2
Patient undergoing elective Common Bile Duct exploration with skin incision longer than 10 cm
Exclusion Criteria
A history of Anesthetic allergy
A history of cardiovascular or pulmonary disease
Renal dysfunction
A history of mental or neurological disease
A history of Radiotherapy or chemotherapy
Alcohol or drug abuse
7.Preoperative medication use that might influence sympathetic responses to surgical incision
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method MAC- BAR of desflurane required to have no hemodynamics during surgical incision.Timepoint: Intraoperative period Dose of inhalational anesthetic desflurane will be increased by 0.25 MAC or decreased by 0.25 MAC based on the hemodynamic response at 1 and 2 minutes after skin incision during intraoperative period.
- Secondary Outcome Measures
Name Time Method Hemodynamic response to skin incision <br/ ><br>BIS value <br/ ><br>Timepoint: Intraoperative period at the time of 1 minute & 2 minutes after surgical incision.