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Promoting Health in Pregnancy and Postpartum

Not Applicable
Completed
Conditions
Overweight
Pregnancy
Obesity
Interventions
Behavioral: Lifestyle Intervention
Behavioral: Standard Care
Registration Number
NCT02260518
Lead Sponsor
University of South Carolina
Brief Summary

The purpose of this study is to examine the impact of a lifestyle intervention on gestational weight gain, postpartum weight loss, and other secondary outcomes relative to a usual care control group.

Detailed Description

Our study will address the following specific aims: (1) examine the impact of a lifestyle intervention on gestational weight gain and postpartum weight loss in overweight and obese women, (2) examine the impact of the intervention on physical activity (PA), dietary intake, and quality of life (QOL), (3) examine race differences in total gestational weight gain, PA, dietary intake, and QOL; and (4) examine the impact of the intervention on offspring adiposity.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
228
Inclusion Criteria
  • White or African American woman
  • Overweight or obese (prepregnancy BMI: 25-45 kg/m2)
  • ≤ 16 wks gestation at screening
  • Age 18-44 years
  • No plan to move out of the greater Columbia area in next 18 months
  • Regular and consistent telephone access
  • Availability for telephone calls
  • Willing to accept random assignment
Exclusion Criteria
  • Uncontrolled hypertension
  • Fetal anomaly
  • Taking insulin for diabetes
  • Uncontrolled or untreated thyroid disease
  • Mental health or substance-abuse hospitalization in last 6 months
  • Multiple gestation
  • Persistent bleeding in the first trimester
  • History of more than 3 miscarriages
  • History of an eating disorder or current eating disorder
  • History of an incompetent cervix
  • Physical disability that prevents exercise
  • Told by health care provider not to exercise
  • Any other medical conditions that might be a contraindication to exercise or dietary change

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Lifestyle InterventionLifestyle InterventionThe intervention will focus on women gaining the recommended amount of weight, increasing physical activity to 150 minutes per week, and meeting healthy eating guidelines.
Standard CareStandard CareWomen in the standard care group will attend their regularly scheduled obstetric (OB) visits with their prenatal care providers and will receive monthly mailings and matched number of podcasts.
Primary Outcome Measures
NameTimeMethod
Gestational weight gain in poundsDelivery

Defined as delivery room weight minus pre-pregnancy weight

Secondary Outcome Measures
NameTimeMethod
Health-Related Quality of Life12 months postpartum

The Short Form-12 (SF-12) questionnaire will be used to assess quality of life.

Dietary intake12 months postpartum

Two 24-hour dietary recalls using the National Cancer Institute's Automated Self-Administered 24-hour Dietary Recall (ASA-24) will assess dietary intake.

Depressive Symptoms12 months postpartum

Depressive symptoms will be assessed with the Edinburgh Prenatal/Postnatal Depression Scale.

Child Adiposity12 months postpartum

Z-scores and skinfolds will be used to measure child adiposity.

Gestational weight gain categoryDelivery

Based on delivery room weight minus pre-pregnancy weight and categorized as Inadequate, adequate, excessive

Postpartum weight retentionWeight retained at the 12 month postpartum visit

Defined as weight during 12 month postpartum visit minus pre-pregnancy weight

Physical Activity12 months postpartum

Sense Wear Armband and self-report measure will assess physical activity

Trial Locations

Locations (1)

University of South Carolina Prevention Research Center

🇺🇸

Columbia, South Carolina, United States

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