Effects of Acetate and Alcohol on Brain Function

Not Applicable

Completed

• Conditions: Brain Function; Cerebral Blood Flow
• Interventions: Drug: alcohol; Drug: acetate

• Registration Number: NCT02542150
• Lead Sponsor: University of Colorado, Denver

Brief Summary

This study plans to learn more about how alcohol and its metabolite, acetate, affect the brain.

Detailed Description

This study plans to learn more about how alcohol and its metabolite, acetate, affect brain function.

Study Timeline

• Study Start: 2015-09
• Study First Submitted: 2015-09-01
• Study First Submitted QC: 2015-09-02
• Study First Posted: 2015-09-04
• Primary Completion: 2017-03-31
• Study Completion: 2017-03-31
• Status Verified: 2021-06
• Results First Submitted: 2021-06-02
• Results First Submitted QC: 2021-06-02
• Last Update Submitted: 2021-06-02
• Results First Posted: 2021-06-25
• Last Update Posted: 2021-06-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

Not provided

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Exclusion Criteria

Not provided

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
alcohol arm	alcohol	jello shots given before magnetic resonance scan
acetate arm	acetate	IV acetate given during magnetic resonance scan

Primary Outcome Measures

Name	Time	Method
Change in Cerebral Blood Flow as Measured With Arterial Spin Labeling	fMRI scan will be scheduled for 1-3 weeks after enrollment. Total visit will be about 6 hrs.	cerebral blood flow is measured during a functional magnetic resonance imaging (fMRI). The reported data reflects best efforts to quantify the collected image data.