Office, Home, and Ambulatory Blood Pressure Measurements in Pediatric Patients
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 52
- 试验地点
- 2
- 主要终点
- Determine blood pressure phenotype
研究概览
简要总结
This will be a prospective observational study. The population would be pediatric patients 6 years to <19 years of age who were referred for elevated blood pressure to investigate if home blood pressure (HBP) can determine blood pressure phenotype (normotensive, hypertensive, masked hypertension, white coat hypertension) as accurately as ambulatory blood pressure monitor (ABPM) in childhood and adolescence.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 6 Years 至 19 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 6 years to <19 years old;
- •Elevated blood pressure defined as 15% lower than the 95%ile BP based on clinical practice guidelines(CPG) but less than stage II hypertension based on CPG;
- •Tolerate ABPM 24 hours;
- •Tolerate HBP; and
- •Can have diabetes mellitus, obstructive sleep apnea, and attention deficit hyperactivity disorder managed by medication.
- •On stable doses of medications known to affect BP such as:
- •Corticosteroids
- •Calcineurin inhibitors
- •Oral decongestants;
- •Clinically stable
排除标准
- •On antihypertension medications or treated in the last 6 months;
- •Structural heart disease such as:
- •Obstructive valvular disease
- •Coarctation of the aorta
- •Cardiomyopathy;
- •Other secondary causes such as:
- •Renal artery stenosis
- •Neurological condition with dysautonomia;
- •Recent initiation of medications known to affect BP such as:
- •Corticosteroids
- •Calcineurin inhibitors
- •Oral decongestants;
结局指标
主要结局
Determine blood pressure phenotype
时间窗: 6-12 months after enrollment
The primary objective of this study is to investigate if home blood pressure (HBP) can determine blood pressure phenotype (normotensive, hypertensive, masked hypertension, white coat hypertension) as accurately as ambulatory blood pressure monitor (ABPM) in childhood and adolescence.
次要结局
- HBP correlation with end organ damage(6-12 months after enrollment)