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Clinical Trials/TCTR20230301004
TCTR20230301004CompletedPhase 2

The efficacy of intraoperative parecoxib with paracetamol for reducing opioid consumption in patient undergoing breast cancer surgery under general anesthesia: A prospective randomized controlled trial

FACULTY OF MEDICINE RESEARCH GRANT KHON KAEN UNIVERSITY0 sites60 target enrollmentStarted: March 1, 2023Last updated:
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Conditions

Trial Snapshot

Phase
Phase 2
Status
Completed
Sponsor
Enrollment
60
Study OverviewEligibility CriteriaInvestigatorsRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

A perioperative combination of intravenous Parecoxib and Paracetamol significantly reduced postoperative morphine consumption during 24 hours and improved the quality of life postoperatively, although without statistically significance

Study Design

Study Type
Interventional

Eligibility Criteria

Ages
18 Years to 65 Years (—)
Sex
Female

Inclusion Criteria

  • •female age 18-65 year
  • •ASA classification 1-3
  • •Patients scheduled for elective breast surgery under general anesthesia at operating room, Srinagarind hospital

Exclusion Criteria

  • •Patients with hypersensitivity or contraindication to the study drugs.
  • •allergy for sulfamethoxazole
  • •History of opioid or steroid (Dexamethasone,Hydrocortisone) used.
  • •Psychologic problems
  • •Operation change
  • •Refuse to participate

Investigators

Sponsor
FACULTY OF MEDICINE RESEARCH GRANT KHON KAEN UNIVERSITY

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