EUCTR2011-002202-70-DE进行中（未招募）不适用
A prospective, non-randomized, mono-center, cohort study to evaluate the effects of 0.5mg intraocular Ranibizumab (Lucentis) injections on retinal function in patients with diabetic macular edema (DME) during twelve months - Ranibizumab short- and long-term effects on retinal function in wAMD
niversitätsklinikum Schleswig-Holstein (UK-SH)0 个研究点开始时间: 2011年6月21日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Diabetic macular edema with center involvement in at least one eye
- •Patients with a central retinal thickness (CRT) > 250 µm
- •Patients with a BCVA of 78-24 EDTRS letters
- •Decrease in vision is due to DME and not due to other causes, in the opinion of the investigator
- •Type 1 or type 2 diabetes mellitus diagnosed 2 years prior to screening
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •1. history or evidence of severe cardiac disease (e.g., NYHA functional class III or IV)
- •2. clinical or medical history uncontrolled hypertension or diabetes
- •3. of unstable angina, acute coronary syndrome, myocardial infarction or revascularization with 6 months
- •4. ventricular tachyarrythmias requiring ongoing treatment
- •5. History or evidence clinically significant peripheral vascular disease, such as intermittent claudication or prior amputation
- •6. Clinically significant impaired renal or hepatic function
- •7. Stroke within 12 month before trial entry.
- •8. Pregnancy
- •9. Known serious allergies to the fluorescein dye use in angiography
- •10. Known contraindications to the components of Lucentis® formulation.Current use of or likely need for systemic medications known to be toxic to the lens, retina or optic nerve, including Deferoxamine, Chloroquine/ hydroxychloroquine (Plaquenil), Tamoxifen, Phenothiazines and Ethambutol
- •11. Known hypersensitivity to ranibizumab or any component of the ranibizumab formulation
研究者
相似试验
进行中（未招募）
1 期
A prospective, non-randomized, mono-center, cohort study to evaluate the short- and long-term effects of 0.5mg intraocular Ranibizumab (Lucentis) injections on retinal function in patients with wet age-related macular degeneration during twelve month - Ranibizumab short- and long-term effects on retinal function in wAMDRetinal function in patients with wet age-related macular degenerationMedDRA version: 12.1Level: LLTClassification code 10067791Term: Wet macular degenerationEUCTR2010-021777-37-DEniversitätsklinikum Schleswig-Holstein (UK-SH)20
尚未招募
Unknown
A single-centre study to check the visual performance and reduction in farsightedness in children with use of DIMSHYP spectacle lensesCTRI/2024/08/072260Dr. Agarwal’s Eye Hospital Limited
招募中
不适用
Applying a high frequency stimulator intended for shoulder pain patientsKCT0002545Chonbuk National University Hospital38
进行中（未招募）
1 期
A study of the antibiotic teicoplanin in adult patients with leukaemia, lymphoma or myeloma.EUCTR2013-004535-72-IETallaght Hospital, Dublin 24, Ireland
招募中
不适用
Safety and Efficacy evaluation of NANOTEX BONE graft along with fibula flap in reconstruction of segmental mandibular defect - A Pilot Clinical TrialCTRI/2022/07/044291Amrita Vishwa Vidyapeetham Amrita Institute of Medical Sciences