Surgical Treatment of Periimplantitis in Patients With Risk Factors: Heavy Smokers, Type 2 Diabetic and Chronic Periodontitis Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Peri-Implantitis
- Sponsor
- Luiz Antonio Pugliesi Alves de Lima
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Radiographic Bone height Gain
- Last Updated
- 7 years ago
Overview
Brief Summary
This study evaluates clinical and radiographic parameters among riks factor groups in patients with periimplantitis. This study will also treat and evaluate the patients response before and after surgical treatment.
Detailed Description
Periimplantitis (PI) is an inflammatory process that results in tissue attachment bone loss around the implant. Periodontal disease, smoke habit and type 2diabetes mellitus have been recognized as potential risk factor indicators that might lead to complications establishment and progression around dental implants. PI treatment predictability has been shown limited and influenced by factors not totally clarified. The aim of this study is to evaluate the reparative response after PI surgical treatment at clinical and radiographic levelsin risk factors patients: type 2 diabetes mellitus, smokers and chronic periodontal disease.
Investigators
Luiz Antonio Pugliesi Alves de Lima
Associate Professor
University of Sao Paulo
Eligibility Criteria
Inclusion Criteria
- •Implants diagnosed with peri-implantitis with boné defects; Probing depth ≥ 4mm; Positive Bleeding on Probing and Suppuration score; Radiographic Bone Loss ≥ 3mm; Generalized Chronic Periodontitis (Armitage, 1999); Heavy Smokers (\> 10 cigarets per day); Type 2 Diabetes Mellitus tipo 2 (ADA, 2005) with HbA1c between 6.5% and 7.5%
Exclusion Criteria
- •Complete Edentulism; Mucosal disease; Alcohol abuse; Systemic disease except type 2 Diabetes Mellitus, that might interfere in periimplantitis progression; Medication intake: anticoagulants, antineoplasics, contraceptives, bisphosphonates and antidepressives; Medication intake in the last 6 months: antibiotics; Medication intake in the last 3 months: antiinflammatories; Aggressive Periodontitis and Anaphylactic shock history; Periodontal treatment in the last 6 months before the baseline; Periodontal Pockets \> 7mm; Light Smokers (\< 10 cigarets/day); Implant Mobility.
Outcomes
Primary Outcomes
Radiographic Bone height Gain
Time Frame: 3 months
Radiographic Bone Height Gain Comparison to baseline 3 months after surgical treatment
Secondary Outcomes
- Periimplant Pocket probing depth(3 months)