Grafting of the Peri-implant Bony Defects Around Immediate Implants Using Xenogenic Versus Alloplastic Sticky Grafts: Randomized Controlled Clinical Trial

Not Applicable

Recruiting

• Conditions: Bone Loss, Alveolar

• Registration Number: NCT06653868
• Lead Sponsor: Cairo University

Brief Summary

In patients with a single non restorable tooth, does filling the peri-implant buccal gap with alloplastic sticky grafts result comparable results compared to xenogenic sticky grafts?

Detailed Description

The buccal aspect of the dental implant has great importance, especially in the aesthetic zone, because the buccal bone is very thin especially in the anterior maxilla and its resorption can result in recession of the soft tissue. A gap occurs in immediately placed implant due to discrepancy between the dimensions of the extraction socket and the implant. Augmentation of the buccal gap decreases the amount of buccal bone resorption and soft tissue recession . Filling the peri-implant defects has been widely discussed to prevent further bone loss. The use of biologic materials such as platelet rich fibrin can enhance the quality of alloplastic bone grafts to give comparable effect when compared to xenogenic grafts.

Study Timeline

• Status Verified: 2024-10
• Study Start: 2024-10-20
• Study First Submitted: 2024-10-21
• Study First Submitted QC: 2024-10-21
• Last Update Submitted: 2024-10-21
• Study First Posted: 2024-10-22
• Last Update Posted: 2024-10-22
• Primary Completion: 2026-03-20
• Study Completion: 2026-03-20

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1. Patients with healthy systemic condition (Mazzotti et al., 2023).

2. Age from 20-50 years old

3. Patients must be free of any systemic disease which could influence the surgical procedure.

4. Tooth involved in the esthetic zone.

5. Sufficient hard and soft tissue volume in vertical and buccolingual direction

6. Natural teeth adjacent to the involved tooth will be required to be free from infection.

7. Controlled oral hygiene.

8. Indication for tooth extraction included (Degidi et al., 2012);

   • Endodontic failures
   • Untreatable caries
   • Non- restorable teeth
   • Vertical root fracture
   • Remaining roots

Exclusion Criteria

• 1.Pregnant females 2.Smokers (Khuller, 2009) 3.Unmotivated and uncooperative patients with poor oral hygiene 4.Patients with habits that may compromise the longevity and affect the result of the study as alcoholism or parafunctional habits.

5.Presence of acute dento-alveolar infection.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
bone changes	6 months	superimposition

Secondary Outcome Measures

Name	Time	Method
pink esthetic score	6 months	soft tissue esthetics

Trial Locations

Locations (1)

Cairo University; 🇪🇬 Cairo, Egypt