NCT01619540已完成不适用
Study of the Valsalva Manœuvre in the Diagnosis of Left Ventricular Failure During Acute Exacerbation of Chronic Obstructive Pulmonary Disease
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 150
- 试验地点
- 4
- 主要终点
- left ventricular dysfunction
研究概览
简要总结
Left ventricular failure (LVF) is a common cause of acute exacerbation of chronic obstructive pulmonary disease (AECOPD).
This association is frequently underestimated with regard to the difficulty of clinical diagnosis .
The investigators expect that Valsalva Maneuver (VM) could be useful in this issue.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •We included in this group, patients with a history (previous history) of COPD who consulted the emergency room for an exacerbation of COPD defined by a respiratory rate> 25c/min and a pH <7.35 and a PaCO2 >6 KPa.
- •This group is also divided into two groups according to clinical expert assessment and the BNP value: Group1 : BNP> 400pg/ml, Group2 : BNP <400PG / ml
排除标准
- •We excluded from this study patients with Prominent cardiac arrest
- •Rhythm disorders including severe tachycardia arrhythmia
- •Auricular fibrillation
- •Hemodynamic instability requiring the use of vasoactive drugs and a contre indications of non invasive ventilation such us consciousness disorders with a Glasgow score <12/15,a swallowing disorder
- •A significant bronchial obstruction ,the upper airway obstruction , in upper gastrointestinal bleeding in progress, an extreme obesity and Cirrhosis or cancer.
- •We are also excluded patients who did not cooperate and those who refused the study.
研究组 & 干预措施
acute heart failure
Other
control arm
干预措施: Valsalva maneuver (Other)
COPD exacerbation
Experimental
COPD exacerbation
干预措施: Valsalva maneuver (Other)
结局指标
主要结局
left ventricular dysfunction
时间窗: 24 hours
次要结局
未报告次要终点
研究者
Nouira
Study of the Valsalva Manœuvre in Diagnoses of Left Ventricular Failure During Acute Exacerbation of Chronic Obstructive Pulmonary Desease
University of Monastir
研究点 (4)
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