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Clinical Trials/NCT04852341
NCT04852341
Completed
Not Applicable

Study on the Difference of Preoperative Related Parameters in Children With or Without Microcornea Within Less Than One Year Old

Wenzhou Medical University1 site in 1 country117 target enrollmentMay 1, 2015

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Microcornea Within One Year of Age
Sponsor
Wenzhou Medical University
Enrollment
117
Locations
1
Primary Endpoint
horizontal diameter of the cornea
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

This subject is mainly to study difference of Congenital cataract preoperative related parameters in children with or without Microcornea within Less than one year old. A total of 186 eyes of 117 people were collected with relevant ocular biological parameters, including age, horizontal diameter of the cornea, Eye axis, intraocular pressure, steep axis of corneal curvature, flat axis of corneal curvature, corneal thickness, lens thickness, anterior chamber depth. At present, because the definition of patients with small cornea is not clear enough, the study subjects are divided into 4 groups according to the horizontal corneal diameter of 9.0mm, 9.5mm, and 10.0mm, namely ≤9.0mm group, 9~9.5mm group, 9.5~10.0mm group and The >10.0mm group compares the differences between each other, and tries to provide a reference for the diagnosis of children with small cornea at a young age.

Registry
clinicaltrials.gov
Start Date
May 1, 2015
End Date
January 1, 2021
Last Updated
5 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Yune Zhao

Deputy Dean

Wenzhou Medical University

Eligibility Criteria

Inclusion Criteria

  • Congenital cataract children with or without Microcornea within Less than one year old
  • Complete collection of eye biological parameters before the first-stage Congenital cataract surgery
  • The nutritional status and development of the included subjects have no obvious defects

Exclusion Criteria

  • congenital persistent pupilary membrane
  • lens sublaxation or lens dislocotion
  • Marfan syndrome
  • Down's Syndrome
  • Peters abnormality
  • history of obvious eye trauma
  • obvious macula
  • long-term (local or systemic) use of glucocorticoids.

Outcomes

Primary Outcomes

horizontal diameter of the cornea

Time Frame: 2015.5.1-2020.12.1

Use a ruler to measure during surgery

Secondary Outcomes

  • steep axis of corneal curvature(2015.5.1-2020.12.1)
  • anterior chamber depth(2015.5.1-2020.12.1)
  • intraocular pressure(2015.5.1-2020.12.1)
  • Eye axis(2015.5.1-2020.12.1)
  • corneal thickness(2015.5.1-2020.12.1)
  • age(2015.5.1-2020.12.1)
  • flat axis of corneal curvature(2015.5.1-2020.12.1)
  • lens thickness(2015.5.1-2020.12.1)

Study Sites (1)

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