Study on the Difference of Preoperative Related Parameters in Children With or Without Microcornea Within Less Than One Year Old
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Microcornea Within One Year of Age
- Sponsor
- Wenzhou Medical University
- Enrollment
- 117
- Locations
- 1
- Primary Endpoint
- horizontal diameter of the cornea
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
This subject is mainly to study difference of Congenital cataract preoperative related parameters in children with or without Microcornea within Less than one year old. A total of 186 eyes of 117 people were collected with relevant ocular biological parameters, including age, horizontal diameter of the cornea, Eye axis, intraocular pressure, steep axis of corneal curvature, flat axis of corneal curvature, corneal thickness, lens thickness, anterior chamber depth. At present, because the definition of patients with small cornea is not clear enough, the study subjects are divided into 4 groups according to the horizontal corneal diameter of 9.0mm, 9.5mm, and 10.0mm, namely ≤9.0mm group, 9~9.5mm group, 9.5~10.0mm group and The >10.0mm group compares the differences between each other, and tries to provide a reference for the diagnosis of children with small cornea at a young age.
Investigators
Yune Zhao
Deputy Dean
Wenzhou Medical University
Eligibility Criteria
Inclusion Criteria
- •Congenital cataract children with or without Microcornea within Less than one year old
- •Complete collection of eye biological parameters before the first-stage Congenital cataract surgery
- •The nutritional status and development of the included subjects have no obvious defects
Exclusion Criteria
- •congenital persistent pupilary membrane
- •lens sublaxation or lens dislocotion
- •Marfan syndrome
- •Down's Syndrome
- •Peters abnormality
- •history of obvious eye trauma
- •obvious macula
- •long-term (local or systemic) use of glucocorticoids.
Outcomes
Primary Outcomes
horizontal diameter of the cornea
Time Frame: 2015.5.1-2020.12.1
Use a ruler to measure during surgery
Secondary Outcomes
- steep axis of corneal curvature(2015.5.1-2020.12.1)
- anterior chamber depth(2015.5.1-2020.12.1)
- intraocular pressure(2015.5.1-2020.12.1)
- Eye axis(2015.5.1-2020.12.1)
- corneal thickness(2015.5.1-2020.12.1)
- age(2015.5.1-2020.12.1)
- flat axis of corneal curvature(2015.5.1-2020.12.1)
- lens thickness(2015.5.1-2020.12.1)