The study is to determine the effect and outcomes of single vs multiple arterial revascularization for patients undergoing coronary artery bypass surgery
- Conditions
- Health Condition 1: I251- Atherosclerotic heart disease of native coronary arteryHealth Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2021/06/034072
- Lead Sponsor
- Weill Medical College of Cornell University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Male or female aged between 18 Years to 70 Years(Adult, Older Adult)
Primary isolated CABG patients with disease of the left main coronary artery and/or of the left anterior descending and the circumflex coronary system with or without disease of the right coronary artery
Able to provide written informed consent
Age > 70 years
Single graft
Emergency operation
Evolving myocardial infarction within 48 hours of surgery
Left ventricular ejection fraction of less than 35%
Any concomitant cardiac or non-cardiac procedure
Previous cardiac surgery
Preoperative severe end-organ dysfunction (dialysis, liver failure, respiratory failure), cancer or any co-morbidity that reduce life expectancy to less than 5 years
Inability to use the saphenous vein or to use both radial and right internal thoracic arteries
Anticipated need for coronary thrombo-endarterectomy
Planned hybrid revascularization
Not able to provide written informed consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Composite Outcome <br/ ><br>A composite of death from any cause, any stroke, post discharge myocardial infarction and/or repeat revascularization <br/ ><br>Timepoint: Time Frame: morethan 72 hours after surgery and/or repeat revascularization <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1.30-day mortality -Death from any cause at 30-days <br/ ><br>2.Major postoperative complications <br/ ><br>3.Sternal wound complication <br/ ><br>4.Composite Outcome of Death from any cause <br/ ><br>5.Stroke <br/ ><br>6.Cause-specific death (cardiac vs non-cardiac) <br/ ><br>7.Hospital readmissions <br/ ><br>Timepoint: 30days to 5 years