The Study of Regional Lung Ventilation-perfusion by EIT

• Conditions: Pulmonary Perfusion; Pulmonary Ventilation

• Registration Number: NCT05105932
• Lead Sponsor: Peking Union Medical College Hospital

Brief Summary

This is a prospective observational trial. The purpose of this study is to explore the feasibility of EIT monitoring pulmonary blood flow and the consistency and difference between EIT monitoring pulmonary local ventilation blood flow and SPECT and CTPA monitoring methods

Detailed Description

Not available

Study Timeline

• Study Start: 2020-01-01
• Study First Submitted: 2021-01-28
• Status Verified: 2021-10
• Study First Submitted QC: 2021-10-24
• Last Update Submitted: 2021-10-24
• Study First Posted: 2021-11-03
• Last Update Posted: 2021-11-03
• Primary Completion: 2023-06-01
• Study Completion: 2023-06-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. Admission to ICU was less than 72 hours;
2. Age ≥ 18 years old and ≤ 80 years old;
3. Volunteer to participate after communicating with patients' family members;

Exclusion Criteria

1. The patients with heart implants could not be monitored by EIT;
2. Patients or their families refused to participate in the study;
3. Hypernatremia

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Regional pulmonary perfusion by EIT	1 Day	Using EIT to measure the regional pulmonary perfusion and calculate ventilation/perfusion ratio
Regional pulmonary perfusion by CTPA	1 Day	Using CTPA to measure the regional pulmonary perfusion and calculate ventilation/perfusion ratio

Secondary Outcome Measures

Name	Time	Method
Regional pulmonary ventilation index by EIT	1 Day	Regional pulmonary ventilation index by EIT, including GI: global inhomogeneity CoV: center of ventilation, ROI: region of interest

Trial Locations

Locations (1)

Peking Union Medical College Hospital; 🇨🇳 Beijing, Beijing, China