NCT03663634已完成不适用
Cytochalasin B Supplementation to ICSI Handling Medium
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 987
- 试验地点
- 1
- 主要终点
- oocyte survival rate
研究概览
简要总结
Vienna Consensus has identified 10% damage rate after ICSI as a competency value. Despite the highest quality embryologists doing ICSI, degeneration sometimes occurs due to oocyte factors such as the fragile membrane, etc. Cytochalasin B serves to facilitate spindle or pronuclear transfer procedures helping to reduce the damage rate with no harm reported. Using Cytochalasin B during ICSI could serve to rescue some oocytes from the degeneration allowing for more chances of viable zygotes,
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •All ICSI candidates patients
排除标准
- •No exclusion
研究组 & 干预措施
Handling Medium Supplemented with Cytochalasin B
Experimental
干预措施: Cytochalasin B use in ICSI handling medium (Other)
Handling Medium as it is.
No Intervention
结局指标
主要结局
oocyte survival rate
时间窗: 6 days of culture
number of survived oocyte after intracytoplasmic sperm injection
次要结局
- fertilization rate(6 days of culture)
- clinical pregnancy rate(three months)
- ongoing pregnancy rate(four months)
- blastocyst formation rate(6 days of culture)
- embryo utilization rate(6 days of culture)
研究者
Muhammad Fawzy
IVF Lab Director
Ibn Sina Hospital
研究点 (1)
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