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A prospective randomized single blind multicenter phase II study of organ perfusion with Custodiol-N compared with Custodiol in heart transplantation in children (CL-N-HTX-Paed-II/10/20)

Phase 1
Recruiting
Conditions
heart transplantation in children
Therapeutic area: Diseases [C] - Cardiovascular Diseases [C14]
Registration Number
CTIS2023-510492-57-00
Lead Sponsor
Dr. Franz Koehler Chemie GmbH
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
15
Inclusion Criteria

Patient criteria: Age from birth to less than18 years, Patient critera: Recipients awaiting their first transplant, Patient criteria: Ability of the patients and/ or their legal guardians to understand character and individual consequences of the clinical trial, Patient criteria: written informed consent of the patients and/ or their legal guardians (must be available before enrolment in the study), Patient criteria: Patient listed on the waiting list for heart transplantation, Donor criteria: deceased donors should fulfil the standard criteria for organ donation (SCD)

Exclusion Criteria

Patients who have participated within 30 days or are still participating in any other interventional studies, history of severe organic disease other than concerning the heart, history/demonstration of HIV antibodies or AIDS, multiorgan transplantation, machine-perfused organ, the explantation team is affiliated to another clinic than transplantation team, Failing Fontan patients, Pregnancy and lactation, Patients who have been incarcerated or involuntarily institutionalized by court order or by the authorities

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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