NL-OMON44732招募中不适用
CD4+ T cells and immune ageing; major players and predictors for disease activity in giant cell arteritis - CD4+ T cells and immune ageing in giant cell arteritis
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,500
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •GCA patients
- •1. Fulfilling ACR criteria for GCA
- •2. Not yet treated with corticosteroids
- •3. Age >= 50 years
- •4. Being able to give informed consent
- •GCA patients in remission
- •1. Fulfilling ACR criteria for GCA
- •2. Age >= 50 years
- •3. Being able to give informed consent ;PMR patients
- •1. Fulfilling Healey criteria for PMR
- •2. Not yet treated with corticosteroids
- •3. Age >= 50 years
- •4. Being able to give informed consent
- •;PMR patients in remission
- •1. Fulfilling Healey criteria for PMR
- •2. Age >= 50 years
- •3. Being able to give informed consent ;Healthy controls
- •1. Having no chronic disease
- •2. Age >= 50 years
- •3. Being healthy according to SENIEUR protocol
- •4. Being able to give informed consent;Infectious controls
- •1. Having no chronic disease
- •2. Age >= 50 years
- •3. Being healthy according to SENIEUR protocol, exept for an urinary tract or upper airway infection
- •4. Being able to give informed consent
排除标准
- •GCA patients
- •1. Not fulfilling the ACR criteria for GCA
- •2. Concomitant chronic diseases that may affect immune system (such as prior or current malignant disease, active infectious disease, other rheumatological disease, kidney disease, active allergy etc.) ;PMR patients
- •1. Not fulfilling Healey criteria for PMR
- •2. Concomitant chronic diseases that may affect immune system (such as prior or current malignant disease, active infectious disease, other rheumatological disease, kidney disease, active allergy etc.) ;Healthy controls
- •1. Having chronic diseases
- •2. Not being healthy according to SENIEUR protocol;Infectious controls
- •1. Having chronic diseases
- •2. Not being healthy according to SENIEUR protocol, except for an urinary or upper airway infection.;GCA patients, PMR patients, healthy and infectious controls
- •1. No informed consent
- •2. Severe anaemia defined as a Hb of less than 6,0 g/dL
研究者
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