MedPath

Reconstruction of the Orbit With a Bioresorbable Polycaprolactone Implant

Phase 2
Completed
Conditions
Orbital Trauma
Orbital Fractures
Registration Number
NCT00233922
Lead Sponsor
National University Hospital, Singapore
Brief Summary

Patients with orbital injuries are entered into the trial. Age: 20 - 70. After obtaining appropriate consent, they are entered into either a control arm where reconstruction of the orbit is done with a titanium mesh (established practice) or the experimental arm where reconstruction is by a bioresorbable implant made of polycaprolactone. Patients are followuped at 1 week, 1 month, 3 months, 6 months \& 12 months. CT scan of the orbits are performed preop, 6 months \& 12 months. End point is the 12 month follow-up appointment. Visual acuity, range of motion, enophthalmos \& diplopia are assessed in follow-up.

Detailed Description

Patients with orbital injuries are entered into the trial. Age: 20 - 70. After obtaining appropriate consent, they are entered into either a control arm where reconstruction of the orbit is done with a titanium mesh (established practice) or the experimental arm where reconstruction is by a bioresorbable implant made of polycaprolactone. Patients are followuped at 1 week, 1 month, 3 months, 6 months \& 12 months. CT scan of the orbits are performed preop, 6 months \& 12 months. End point is the 12 month follow-up appointment. Visual acuity, range of motion, enophthalmos \& diplopia are assessed in follow-up.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
80
Inclusion Criteria
  • age: 20 - 70 years facial trauma with orbital fractures
Exclusion Criteria
  • No other coexistent conditions eg. diabetes, heart disease, etc

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
visual acuity
Enophthalmos
Diplopia
Cosmetic appearance
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

National University Hospital

🇸🇬

Singapore, Singapore

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