Comparison of the Use of Energy Substrates and Hormonal Regulation of Blood Sugar During Exercise of Increasing Intensity Between Children With Type 1 Diabetes and Non-diabetic Control Children.
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 48
- 试验地点
- 1
- 主要终点
- Comparison of substrate utilization between infants with type 1 diabetes and infants without type 1 diabetes during exercise
研究概览
简要总结
The type 1 diabetes is a common chronic disease characterised by the stop of production of insulin by the pancreas. A lot of factors modify blood glucose. The objective is to study the effect of type 1 diabetes on the use of energy substrates (fats and carbohydrates) during exercise of increasing intensity by a comparison with non-diabetic controls children.
详细描述
The type 1 diabetes is a common chronic disease characterised by the stop of production of insulin by the pancreas. A lot of factors modify blood glucose. The objective is to study the effect of type 1 diabetes on the use of energy substrates (fats and carbohydrates) during exercise of increasing intensity by a comparison with non-diabetic controls children.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
盲法说明
no masking is used. All involved know the identity of the intervention assignment
入排标准
- 年龄范围
- 6 Years 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Children between 6 and 12 years
- •Tanner stage <T2
- •Type 1 diabetes for more than 1 year for infants with type 1 diabetes
排除标准
- •Tanner stage > ou = T2
- •Hormonal disease
- •Disease who prevent doing exercise
研究组 & 干预措施
type 1 diabetes
Comparison between infants with type 1 diabetes and infants without type 1 diabetes during exercise :
干预措施: controlled physical activity (Procedure)
without type 1 diabetes
Comparison between infants with type 1 diabetes and infants without type 1 diabetes during exercise :
干预措施: controlled physical activity (Procedure)
结局指标
主要结局
Comparison of substrate utilization between infants with type 1 diabetes and infants without type 1 diabetes during exercise
时间窗: at day 1
Measurements will be carried out by indirect calorimetry and the relationship between CO2 et O2 (Metamax)
次要结局
- hormonal regulation of blood glucose(at day 1)
- lipoxmax : the intensity for wich lipid oxydation is maximum will be carried out by indirect calorimetry(at day 1)
- Comparison between infants during 10 days before and 4 days after exercise of blood glucose modification(10 days before and 4 days after exercise of blood glucose modification)