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Clinical Trials/NCT04851886
NCT04851886
Not yet recruiting
Not Applicable

PostureCheck: A Vision-based Compensatory-posture-detection Tool to Enhance Performance of the BURT Upper-extremity Stroke-therapy

Spaulding Rehabilitation Hospital0 sites42 target enrollmentSeptember 1, 2023
ConditionsStroke

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Stroke
Sponsor
Spaulding Rehabilitation Hospital
Enrollment
42
Primary Endpoint
Change from baseline Fugl-Meyer Assessment - Upper Extremity (FMA-UE) at 7-8 weeks
Status
Not yet recruiting
Last Updated
2 years ago

Overview

Brief Summary

The overall objective of this study is to assess whether robot-assisted upper-limb group rehabilitation can be effectively delivered by using a camera-based system equipped with machine learning algorithms to track the quality of the exercise performance and provide feedback accordingly. To address this question, we plan to carry out a randomized clinical trial to compare outcomes in subjects receiving robot-assisted upper-limb rehabilitation during individual (i.e., one-on-one) sessions and in subjects receiving robot-assisted upper-limb rehabilitation during group (i.e., up to three subjects) sessions.

Detailed Description

The proposed study is a single-blinded randomized clinical trial to evaluate the effect of using the PostureCheck (a camera-based system equipped with machine learning algorithms to track the quality of the exercise performance) on motor gains in group and individual robot-assisted upper-limb. Study participants (stroke survivors) will be recruited at the Spaulding Rehabilitation Hospital - Boston. Subjects will be randomly assigned to one of the two different groups: individual- or group-therapy using a covariate-adaptive allocation procedure to ensure important covariates, such as baseline Fugl-Meyer Assessment of the Upper Extremity (FMA-UE) scores and proprioceptive deficits, are balanced between groups.

Registry
clinicaltrials.gov
Start Date
September 1, 2023
End Date
December 31, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Spaulding Rehabilitation Hospital
Responsible Party
Principal Investigator
Principal Investigator

Paolo Bonato

Director, Motion Analysis Laboratory

Spaulding Rehabilitation Hospital

Eligibility Criteria

Inclusion Criteria

  • Have had a history of ischemic cerebrovascular accident (CVA) within middle cerebral artery (MCA) or anterior cerebral artery (ACA) territory
  • CVA occurred between six months and six years ago
  • Moderate to severe UE impairment, FMA-UE score between 15 and 45
  • Mini-Mental State Examination (MMSE) score \>23 and being able to safely follow three-step commands

Exclusion Criteria

  • Advanced musculoskeletal pathology or recent fractures in the impaired UE
  • Previous diagnosis of neurological diseases other than stroke
  • Severe limitation of passive range of motion or spasticity (Modified Ashworth Scale for spasticity at \<3 for UE muscles)
  • Hemorrhagic CVA or involvement of the posterior cerebral artery
  • Aphasia sufficient to limit ability to express needs or discomfort verbally or non-verbally
  • Impaired visual acuity (Severe visual impairments as assessed by the NIH Stroke Scale Visual Field subscale. (score \>0))
  • Severe hemispatial neglect as assessed by the Line Bisection Test (score \>2)
  • Severely impaired trunk control (\<4)
  • Individuals who present with the following on the intended limb:
  • Open wounds

Outcomes

Primary Outcomes

Change from baseline Fugl-Meyer Assessment - Upper Extremity (FMA-UE) at 7-8 weeks

Time Frame: Data will be collected at baseline and at 7-8 weeks

Standard assessment of the severity of upper-limb motor impairments

Secondary Outcomes

  • Change from baseline Motor Activity Log (MAL) at 7-8 weeks(Data will be collected at baseline and at 7-8 weeks)
  • Change from baseline Wolf Motor Function Test (WMFT) at 7-8 weeks(Data will be collected at baseline and at 7-8 weeks)

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