Sonographic Evaluation of Patients With Carpal Tunnel Syndrome Following Steroid Injection
试验速览
- 阶段
- 不适用
- 入组人数
- 54
- 试验地点
- 1
- 主要终点
- Cross sectional area
研究概览
简要总结
The objective of this study was to assess sonographic changes of the median nerve after steroid injection for carpal tunnel syndrome.
详细描述
Patients with CTS were recruited. The Boston Questionnaire (BQ) was administered and ultrasonographic and electrophysiological examinations were performed before and at two, six, and 12 weeks after steroid injection. Cross sectional area (CSA) was measured at 2 levels: at the tunnel inlet and in the mid-carpal tunnel. Flattening ratio (FR) was measured only in the mid-carpal tunnel. Correlation analyses between baseline ultrasonography, BQ, and electrophysiological measures were performed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •clinical diagnosis of CTS
- •The diagnosis of CTS was confirmed by electrophysiological tests.
排除标准
- •neurologic disorders that could mimic CTS such as cervical radiculopathy, polyneuropathy, proximal median nerve entrapment, or thoracic outlet syndrome
- •history of distal radius fracture
- •pregnancy or lactation
- •regular use of systemic NSAIDs or corticosteroids
- •known allergy to corticosteroids and local anesthetics.
研究组 & 干预措施
steroid injection
ultrasound-guided steroid injection using 1ml of 10 mg (10mg/ml) triamcinolone acetonide
干预措施: steroid injection (Drug)
结局指标
主要结局
Cross sectional area
时间窗: 12 weeks
The CSA of the median nerve was measured at 2 levels: at the carpal tunnel inlet (CSA-I; immediately prior to the proximal margin of the flexor retinaculum) and in the mid-carpal tunnel (CSA-M; at the level of the pisiform bone and scaphoid tubercle)
次要结局
- flattening ratio(2, 6, 12 weeks)
- Boston Carpal Tunnel Questionnaire (BQ)(2, 6, 12 weeks)
- Median nerve distal motor latency(2, 6, 12 weeks)
- sensory nerve conduction velocity(2, 6, 12 weeks)
- compound muscle action potential amplitude (CMAP)(2, 6, 12 weeks)
- sensory nerve action potential amplitudes.(2, 6, 12 weeks)