Assessment of Rapid Osseointegration of Dental Implants with Different Coatings

Not Applicable

Completed

• Conditions: Dental Implants; Hyaluronic Acid

• Registration Number: NCT06650280
• Lead Sponsor: October University for Modern Sciences and Arts

Brief Summary

The study will assess early osseointegration of dental implant with three different coating materials through secondary implant stability

Detailed Description

Dental implants with sandblasted acid itched coating, nano-hydroxyapatite coating, and hyalouronic acid coating will be placed in the posterior maxilla to restore a missing tooth. Implant stability by the use of Ostell will be measured immediately post-operative, 4, 6, and 12 weeks post-operative.

marginal bone loss around the implants will be compared immediately after final restoration delivery and after one year

Study Timeline

• Study Start: 2023-02-01
• Primary Completion: 2024-02-01
• Study Completion: 2024-06-01
• Status Verified: 2024-10
• Study First Submitted: 2024-10-17
• Study First Submitted QC: 2024-10-18
• Last Update Submitted: 2024-10-18
• Study First Posted: 2024-10-21
• Last Update Posted: 2024-10-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

1. Patients with missing at least one maxillary posterior tooth
2. Patients free from any systemic disease
3. Patients who approve to be included in the trial and sign the informed consent
4. Patients with no intra-bony defect.
5. Adults aged 18 years old and above

Exclusion Criteria

1. Patients who are allergic to titanium
2. Heavy smoker patient
3. Patients receiving chemotherapy or radiotherapy
4. Patients who refused to be included in the trial

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
rapid osseintegration	immediately post-operative, 4, 6, and 12 weeks post-operative	rapid osteointegration of dental implants will be evaluated by the use of Ostell device which measures primary and secondary stability expressed as ISQ measures ranging from zero till 90

Secondary Outcome Measures

Name	Time	Method
marginal bone loss	immediately after final restoration delivery and one year post-operative	the bone height from implant's platform till implant's tip will be measured and compared between immediately after final restoration delivery and after one year

Trial Locations

Locations (1)

Faculty of Dentistry, MSA University; 🇪🇬 Giza, Egypt