Swiss National Iodine Survey 2015

Completed

• Conditions: Healthy Subjects

• Registration Number: NCT02312466
• Lead Sponsor: Isabelle Herter-Aeberli

Brief Summary

The aim of this study is to monitor iodine nutrition in Switzerland in order to inform the authorities regarding iodine content in iodized salt. As a proxy for the entire population the investigators will study school aged children, pregnant women and women of reproduction age.

Detailed Description

In a national sample of school aged children (n=990), pregnant women (n=700) and women of reproductive age (n=700) urinary iodine will be determined in order to assess iodine nutrition in Switzerland. In addition, in both groups of women a blood sample will be taken for the determination of thyroid hormones, iron- and folate status. Questionnaires will be used for the determination of dietary iodine and salt intake as well as sociodemographic parameters.

Study Timeline

• Study First Submitted: 2014-12-03
• Study First Submitted QC: 2014-12-05
• Study First Posted: 2014-12-09
• Study Start: 2015-03
• Primary Completion: 2016-09
• Study Completion: 2016-12
• Status Verified: 2020-09
• Last Update Submitted: 2020-09-15
• Last Update Posted: 2020-09-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1430

Inclusion Criteria

• Healthy
• Living in Switzerland for at least 1 year
• For pregnant women: singleton pregnancy

Exclusion Criteria

• Major known medical illness: thyroid dysfunction, gastrointestinal or metabolic disorders and taking chronic medications
• For women of reproductive age: pregnancy, breastfeeding
• Use of X-ray or CT contrast agent or iodine containing medication within the past year

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Median urinary iodine concentration in school aged children, pregnant women and women of reproductive age	Baseline	analysis of urine samples

Secondary Outcome Measures

Name	Time	Method
Median urinary creatinin concentration	Baseline
Population mean thyroglobulin	Baseline	Analysis of venous blood samples. Assessed only in women
Median urinary sodium concentration	Baseline
Population mean thyroxine	Baseline	Analysis of venous blood samples. Assessed only in women
Population mean thyroid stimulating hormone	Baseline	Analysis of venous blood samples. Assessed only in women

Trial Locations

Locations (1)

Human Nutrition Laboratory, ETH Zurich; 🇨🇭 Zurich, Switzerland