Comparison of Analgesic Efficacy of Preemptive Ultrasound Guided Transversus Abdominis Plane Block and Preemptive Subcutaneous Infiltration of incision site in abdominal surgeries(below T8 level):A Prospective randomised comparative study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To compare the total morphine consumption in both groups in the first 24hours following surgery
研究概览
简要总结
Pain is an important hindrance to recovery from surgery and anaesthesia in the post-operative period. Abdominal incisions are commonly associated with persistant post-operative pain,affects respiratory function and also associated with increased analgesic requirement.
Opioids are the main stay of treatment for postoperative pain,even though opioids are the most effective forms of medication that are being used in relieving pain they are associated with severe systemic side effects.
Therefore,a general goal is to minimize exposure to the side effects of prolonged systemic narcotics while ensuring adequate pain relief.
Preemptive analgesia is defined as "treatment initiated before the surgical procedure in order to prevent establishment of central senstitization evoked by the incisional and inflammatory injuries occuring during surgery and in the early post-operative period".
Effective preemptive analgesic technique requires multimodal interception of pain perception,increasing threshold for nociception and decreasing or blocking pain receptor activation.Because of this protective effect on the nociceptive systems,preemptive analgesia has the potential to be more efficient than analgesic treatment initiated after surgery
This study will be done to evaluate and compare the usefulness of TAP block versus subcutaneous infiltration as preemptive analgesia in abdominal surgeries below T8 level
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients of either sex, with ASA physical status grade I, II and III.
- •Patients scheduled to undergo abdominal surgeries with incisions from or below T8 dermatomal level.
排除标准
- •1.Patients who are not willing to participate in the study.
- •3.Patients with morbid obesity (BMI more than 35 kg/m2).
- •4.Patients with previous abdominal surgeries.
- •5.Patients with hepatic, renal, cardiac and seizure disorders.
- •6.Pregnant and lactating women.
- •7.Patients who cannot understand or interpret VAS for pain assessment.
- •8.Patients who could not be extubated on table.
结局指标
主要结局
To compare the total morphine consumption in both groups in the first 24hours following surgery
时间窗: Total morphine dosage requirement according to VAS score will be noted as per patient requirement within 24 hours of post operative period
次要结局
- 1.To determine the effect of preemptive analgesia on the hemodynamic response to surgical incision in both groups(2.To assess magnitude of pain by Visual analogue scale at different time points)
研究者
Dr Revelli Mounika
SRI VENKATESWARA INSTITUTE OF MEDICAL SCIENCES