Endovascular Treatment of Wide Neck Saccular Cerebral Aneurysms
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Wide Neck Saccular Cerebral Aneurysms
- Sponsor
- Sohag University
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- efficacy of procedure
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
Intracranial aneurysm (IA) is a cerebrovascular disorder in which the weakness of a cerebral artery wall causes a localized dilation of the blood vessel. Intracranial aneurysm can develop and rupture, and about 85% of spontaneous subarachnoid hemorrhage (SAH) cases are caused by the rupture of Intracerebral aneurysm.
Two treatments are available globally: microsurgical clipping and endovascular treatment.
Endovascular treatment of Intracerebral aneurysms using detachable platinum coils ( was introduced in 1990 by Guido Guglielmi, an Italian neurosurgeon ) of different shapes and sizes are deposited into the aneurysm through a microcatheter, which reduces the blood flow and induces thrombus formation .
Wide neck aneurysm defined by neck diameter greater than 4 mm or dome-to-neck ratio less than 2 Despite advances in endovascular techniques , the treatment of wide-necked aneurysms remains problematic . Endovascular treatment of intracranial aneurysms is associated with lower morbidity and mortality rates and faster recovery compared with traditional microsurgical clipping.
In wide-necked Intracerebral aneurysms, complete coil embolization is often technically difficult owing to the risks of distal coil migration or coil impingement on the parent vessel .
Complete coil embolization using a single microcatheter without a supporting device in cases of wide-necked Intracerebral aneurysm is technically difficult. Total occlusion rates have increased recently as a result of the advancement of supporting devices These may include balloon remodeling, use of three-dimensional (3D) coils (Russian Doll Technique), combined use of stents and coils (Stent assisted coiling), flow diverters, use of intrasaccular flow disruption (like WEB), Double catheter Technique or combined extra- and intrasaccular devices.
Investigators
Mohamed Ayman Mohamed
Assistant lecturer of neurosurgery
Sohag University
Eligibility Criteria
Inclusion Criteria
- •All patients of spontaneous subarachnoid haemorrhage due to ruptured wide neck saccular cerebral aneurysms
- •unruptured Denovo wide neck saccular cerebral aneurysms
Exclusion Criteria
- •other forms of cerebral aneurysms rather than saccular type : fusiform and dissecting aneurysms
- •complex aneurysms : giant and thrombosed aneyrsms
- •any spontaneous subarachnoid haemorrhage with world fedriation of neurosurgery societies (WFNS) Grade 4\&5
- •Any patient unfit for general anesethia or has serious renal impairment
Outcomes
Primary Outcomes
efficacy of procedure
Time Frame: 1 year
degree of aneurysm occlusion classifeid by Raymond Roy classification