Retrospective Evaluation of the Effectiveness of Oral Pentosan Polysulfate Treatment in the Improvement of Chronic Interstitial Cystitis Symptoms
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 37
- 试验地点
- 4
- 主要终点
- improvement of lower urinary tract symptoms
研究概览
简要总结
To examine the relationship between symptoms and quality of life before and after oral pentosan polysulfate (PPS) treatment in cases diagnosed with interstitial cystitis/painful bladder syndrome (IC/BPS).
详细描述
Demographic characteristics, medical history, clinical conditions, and laboratory and cystoscopic data of patients who applied to our clinic between January 2018 and December 2021 and were diagnosed with IC/BPS were retrospectively analyzed. Adult male and female patients with IC/BPS who received 300 mg/day PPS at least six months ago with complaints of pain, urge, frequency, and nocturia not associated with urinary tract infection were included in the study. In addition, pre- and post-treatment symptoms, ICSI scores, quality of life (scored between 1-4), and satisfaction were compared.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Sequential
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Chronic interstitial cystitis
- •Bladder Pain Syndrome
排除标准
- •Acute cystitis
- •Bladder cancer
- •Chronic prostatitis
- •Bladder stone
- •Stress incontinence
结局指标
主要结局
improvement of lower urinary tract symptoms
时间窗: Three months
1 if symptoms improved, 0 if not
bladder wall thickness
时间窗: Three months
0.3 over 3 mm 1 under 3 mm,
次要结局
未报告次要终点
研究者
Basri Cakiroglu
Principal Investigator
Hisar Intercontinental Hospital