Cerebral lateralization of ankle joint position sense in healthy left- and right-side dominant adults studied by functional magnetic resonance imaging
Not Applicable
- Conditions
- Healthy people
- Registration Number
- JPRN-UMIN000040959
- Lead Sponsor
- Tohoku University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
history of neurological or orthopaedic disorders other diseases injury claustrophobia anything against performing MRI
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method We will adopt a conventional two-level approach for a block-design fMRI data using SPM12. A voxel-by-voxel multiple regression analysis will be conducted for the first-level within-subject (fixed effects) model. We will construct for each subject a model of expected signal changes involving the four conditions; 2 measurement conditions(ipsilateral/contralateral) by 2 foot-laterality conditions(right/left).
- Secondary Outcome Measures
Name Time Method Any deviation from the target position, discounting direction, was defined as the absolute position error: 1) E absolute = ABS(Xparticipant - Xtarget) For constant error, the difference between reproduced and actual target angle was used, considering the direction of the error: 2) E constant = ( Xparticipant - Xtarget ) 3) E variable: The variable error was calculated as the overall standard deviation (SD) of constant error from 14 trials, irrespective of the target range: