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Chronic and Acute Effects of Artificial Colourings and Preservatives on Children's Behaviour

Completed
Conditions
Hyperactivity
Mental and Behavioural Disorders
Registration Number
ISRCTN74481308
Lead Sponsor
niversity of Southampton (UK)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
297
Inclusion Criteria

Stage 1 - Chronic exposure - 120 three year old children and 120 eight year old children from the general population.
Stage 2 - Acute exposure - 45 eight year old children selected as being responders or non-responders in the Stage 1 challenge.

Exclusion Criteria

Those on special diets.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1. Direct observation of classroom behaviour<br>2. Parent and teacher ratings of hyperactive behaviour<br>3. Continuous performance test assessment of sustained attention
Secondary Outcome Measures
NameTimeMethod
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